Ephrin B2 Protein (EFNB2) (Soluble) (His tag)
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- 抗原 See all Ephrin B2 (EFNB2) 蛋白
- Ephrin B2 (EFNB2)
- 蛋白类型
- Recombinant
- 产品特性
- Soluble
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Ephrin B2 protein is labelled with His tag.
- 原理
- Ephrin-B2, soluble
- 序列
- MIVLEPIYWN SSNSKFLPGQ GLVLYPQIGD KLDIICPKVD SKTVGQYEYY KVYMVDKDQA DRCTIKKENT PLLNCAKPDQ DIKFTIKFQE FSPNLWGLEF QKNKDYYIIS TSNGSLEGLD NQEGGVCQTR AMKILMKVGQ DASSAGSTRN KDPTRRPELE AGTNGRSSTT SPFVKPNPGS STDGNSAGHS GNNILGSEVA LFALEHHHHH H
- 产品特性
- Length (aa):211
- 纯度
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product EFNB2 蛋白
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Ephrin B2 (EFNB2) (AA 28-229) protein (Fc Tag)
EFNB2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Ephrin B2 (EFNB2) (AA 28-127) protein (GST tag)EFNB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Ephrin B2 (EFNB2) protein (His tag,Fc Tag)EFNB2 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
Ephrin B2 (EFNB2) (AA 1-333) protein (GST tag)EFNB2 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
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- 抗原
- Ephrin B2 (EFNB2)
- 别名
- Ephrin-B2 (EFNB2 产品)
- 背景
- EPH-related receptor tyrosine kinase ligand 5, HTK ligand,The large families of Eph receptor tyrosine kinases and their Ephrin ligands transduce signals in a cell-cell contact-dependent fashion. They thereby coordinate the growth, differentiation, and patterning of almost every organ and tissue. Eph/Ephrin interactions can trigger a wide array of cellular responses, including cell adhesion, boundary formation, and repulsion. The exact mechanisms leading to this diversity of responses are unclear but appear to involve differential signaling, proteolytic cleavage of Ephrins, and endocytosis of the ligand-receptor complex. In the developing cardiovascular system, Eph and Ephrin molecules control the angiogenic remodeling of blood vessels and lymphatic vessels and play essential roles in endothelial cells as well as in supporting pericytes and vascular smooth muscle cells. Recent evidence suggests that Ephs and Ephrins may also be involved in pathological angiogenesis, in particular, the neovascularization of tumors. Consequently, the expression, interactions, or signaling of Eph/Ephrin molecules might be targets for future therapeutic approaches. Ephrins are naturally divided into two structural groups. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. This conserved sequence consists of approximately 125 amino acids and includes four invariant cysteines. The B-class ligands are transmembrane proteins, which can be tyrosine phosphorylated upon receptor ligation. Class B ephrins show 33 % amino acid sequence identity in their extracellular segments and 44 % amino acid sequence identity in their cytoplasmic regions.
- 分子量
- 23.4 kDa
- 基因ID
- 1948
- NCBI登录号
- NM_004093, NP_004084
- UniProt
- P52799
- 途径
- RTK signaling, Regulation of Muscle Cell Differentiation
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