PLAP Protein (AA 21-504) (His tag)
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Quick Overview for PLAP Protein (AA 21-504) (His tag) (ABIN7538476)
抗原
See all PLAP (ALPP) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 21-504
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标记
- This PLAP protein is labelled with His tag.
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原理
- Recombinant Cynomolgus ALPP protein with C-terminal 10xHis tag
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特异性
- ALPP (Ile21-Asp504) 10xHis tag
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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别名
- ALPP
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背景
- The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Aug 2020]
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分子量
- predicted molecular mass of 54.1 kDa after removal of the signal peptide. The apparent molecular mass of cALPP-His is 55-70 kDa due to glycosylation.
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NCBI登录号
- XP_045223825
抗原
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