PLAP Protein (AA 23-505) (His tag)
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Quick Overview for PLAP Protein (AA 23-505) (His tag) (ABIN7491369)
抗原
See all PLAP (ALPP) 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 23-505
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标记
- This PLAP protein is labelled with His tag.
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原理
- Recombinant Human ALPP Protein with C-terminal 6xHis tag
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特异性
- ALPP(Ile23-Thr505) 6xHis tag
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Placental Alkaline Phosphatase (ALPP) (AA 1-535) protein (GST tag)
ALPP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Placental Alkaline Phosphatase (ALPP) (AA 21-504) protein (His tag)ALPP 宿主: Cynomolgus 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Placental Alkaline Phosphatase (ALPP) (AA 23-506) (Active) protein (His tag)ALPP 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % SDS, EAA Active
Placental Alkaline Phosphatase (ALPP) protein (Myc-DYKDDDDK Tag)ALPP 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- PLAP (ALPP) (Placental Alkaline Phosphatase (ALPP))
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别名
- ALPP
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背景
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ALP,ALPI,IAP,PALP,PLAP,PLAP-1
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells. [provided by RefSeq, Aug 2020] -
分子量
- predicted molecular mass of 53.5 kDa after removal of the signal peptide. The apparent molecular mass of ALPP-His is 55-70 kDa due to glycosylation.
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UniProt
- P05187
抗原
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