TGFA 蛋白
Quick Overview for TGFA 蛋白 (ABIN7536426)
抗原
See all TGFA 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human TGF-alpha/TGFA Protein
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序列
- VVSHFNDCPD SHTQFCFHGT CRFLVQEDKP ACVCHSGYVG ARCEHADLLA
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特异性
- Val40-Ala89
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过滤
- 0.22 μm filtered
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内毒素水平
- <1EU/μg
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Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (Fc Tag)
TGFA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 39-88) protein (Fc Tag)TGFA 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Transforming Growth Factor, alpha (TGFA) (AA 40-89) protein (His tag)TGFA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Transforming Growth Factor, alpha (TGFA) (AA 1-159) protein (GST tag)TGFA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
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浓度
- 0.3 mg/mL
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缓冲液
- Lyophilized from a 0.22 μm filtered solution of 50 mM Tris,100 mM NaCl, pH 8.0
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储存条件
- -20 °C,-80 °C
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储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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别名
- TGF-alpha/TGFA
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背景
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Description: The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared to adjacent normal tissue and high TGFA gene expression strongly correlated with poor survival in patients with lung adenocarcinoma, and miR-374a suppresses lung adenocarcinoma cell proliferation and invasion via targeting TGFA gene expression. Transforming growth factor alpha (TGFA) is a well-characterized mammalian growth factor that might contribute to the development of Cleft lip and palate (CL/P).
Name: TFGA,TGF-alpha
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基因ID
- 7039
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UniProt
- P01135-1
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途径
- NF-kappaB Signaling, RTK signaling, EGFR Signaling Pathway
抗原
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