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PIN1 蛋白

This Recombinant PIN1 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7533720
发货至: 中国

Quick Overview for PIN1 蛋白 (ABIN7533720)

抗原

See all PIN1 蛋白
PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

蛋白类型

Recombinant

生物活性

Active

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % by SDS-PAGE.
  • 原理

    Active Recombinant Human PIN1 Protein

    序列

    MADEEKLPPG WEKRMSRSSG RVYYFNHITN ASQWERPSGN SSSGGKNGQG EPARVRCSHL LVKHSQSRRP SSWRQEKITR TKEEALELIN GYIQKIKSGE EDFESLASQF SDCSSAKARG DLGAFSRGQM QKPFEDASFA LRTGEMSGPV FTDSGIHIIL RTE

    特异性

    Met1-Glu163

    过滤

    0.22 μm filtered

    内毒素水平

    < 0.1 EU/μg of the protein by LAL method.

    Biological Activity Comment

    Measured by its binding ability in a functional ELISA. Immobilized Human CTNNB1 Protein at 2 μg/mL (100 μL/well) can bind PIN1 with a linear range of 7.8-164.3 ng/mL.
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Human
    价格从 115,504.49 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Human
    价格从 172,528.32 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

    缓冲液

    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store the lyophilized protein at -20°C to -80 °C for long term.
    After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
  • 抗原

    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

    别名

    PIN1

    背景

    Description: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This protein is a nucleus protein which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers.

    Name: PIN1,DOD,UBL5

    基因ID

    5300

    UniProt

    Q13526
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