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MAPT Protein (Fc Tag)

MAPT 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % by SDS-PAGE.
产品编号 ABIN7536499
发货至: 中国
  • 抗原 See all MAPT 蛋白
    MAPT (Microtubule-Associated Protein tau (MAPT))
    蛋白类型
    Recombinant
    宿主
    • 52
    • 1
    • 1
    • 1
    • 1
    资源
    • 47
    • 4
    • 4
    HEK-293 Cells
    标记
    This MAPT protein is labelled with Fc Tag.
    原理
    Recombinant Human Microtubule-associated protein tau/MAPT Protein
    序列
    QAAAQPHTEI PEGTTAEEAG IGDTPSLEDE AAGHVTQARM VSKSKDGTGS DDKKAKGADG KTKIATPRGA APPGQKGQAN ATRIPAKTPP APKTPPSSGE PPKSGDRSGY SSPGSPGTPG SRSRTPSLPT PPTREPKKVA VVR
    特异性
    Gln88-Arg230
    纯度
    > 97 % by SDS-PAGE.
    过滤
    0.22 μm filtered
    内毒素水平
    < 0.01EU/μg
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    Discover our top product MAPT 蛋白
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  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
    浓度
    0.71 mg/mL
    缓冲液
    Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
  • 抗原
    MAPT (Microtubule-Associated Protein tau (MAPT))
    别名
    Microtubule-associated protein tau/MAPT (MAPT 产品)
    背景

    Description: Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. Tau protein is a highly soluble microtubule-associated protein (MAP). In humans, these proteins are mostly found in neurons compared to non-neuronal cells. One of tau's main functions is to modulate the stability of axonal microtubules. Other nervous system MAPs may perform similar functions, as suggested by tau knockout mice, who did not show abnormalities in brain development - possibly because of compensation in tau deficiency by other MAPs.

    Name: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, tau-40, FTDP-17, PPP1R103, Tau-PHF6

    基因ID
    4137
    UniProt
    P10636-8
    途径
    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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