FZD2 Protein (Fc Tag,His tag)
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- 抗原 See all FZD2 蛋白
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This FZD2 protein is labelled with Fc Tag,His tag.
- 原理
- Recombinant Human Frizzled-2/FZD2 Protein
- 序列
- QFHGEKGISI PDHGFCQPIS IPLCTDIAYN QTIMPNLLGH TNQEDAGLEV HQFYPLVKVQ CSPELRFFLC SMYAPVCTVL EQAIPPCRSI CERARQGCEA LMNKFGFQWP ERLRCEHFPR HGAEQICVGQ NHSEDGAPAL
- 特异性
- Gln24-Leu163
- 纯度
- > 95 % by SDS-PAGE.
- 过滤
- 0.22 μm filtered
- 内毒素水平
- < 1 EU/μg of the protein by LAL method.
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- Discover our top product FZD2 蛋白
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Frizzled Family Receptor 2 (FZD2) (AA 24-156) protein (Fc Tag)
FZD2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Frizzled Family Receptor 2 (FZD2) (AA 24-190) protein (Fc Tag)FZD2 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- 缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
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- 抗原
- FZD2 (Frizzled Family Receptor 2 (FZD2))
- 别名
- Frizzled-2/FZD2 (FZD2 产品)
- 背景
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Description: Frizzled-2 (FZD2) is also known as FzE2, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD2 contains one FZ (frizzled) domain. FZD2 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. The Lys-Thr-X-X-X-Trp motif of FZD2 interacts with the PDZ doman of Dvl (Disheveled) family members and is involved in the activation of the Wnt/beta-catenin signaling pathway.
Name: Fz2, fz-2, fzE2, hFz2, OMOD2,FZD2
- 基因ID
- 2535
- UniProt
- Q14332
- 途径
- WNT signaling
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