CD8 alpha Protein (Fc Tag)
Quick Overview for CD8 alpha Protein (Fc Tag) (ABIN7535717)
抗原
See all CD8 alpha (CD8A) 蛋白蛋白类型
宿主
资源
纯度
-
-
标记
- This CD8 alpha protein is labelled with Fc Tag.
-
原理
- Recombinant Mouse CD8a Protein
-
序列
- KPQAPELRIF PKKMDAELGQ KVDLVCEVLG SVSQGCSWLF QNSSSKLPQP TFVVYMASSH NKITWDEKLN SSKLFSAMRD TNNKYVLTLN KFSKENEGYY FCSVISNSVM YFSSVVPVLQ KVNSTTTKPV LRTPSPVHPT GTSQPQRPED CRPRGSVKGT GLDFACDIY
-
特异性
- Lys28-Tyr196
-
过滤
- 0.22 μm filtered
-
内毒素水平
- <0.1EU/μg
-
-
CD8a Molecule (CD8A) (AA 28-196) protein (His tag)
CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD8a Molecule (CD8A) (AA 22-182) protein (His-Avi Tag,Biotin)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) (Active) protein (His tag,AVI tag,Biotin)CD8A 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD8a Molecule (CD8A) (AA 22-182) protein (His-IF2DI Tag)CD8A 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
CD8a Molecule (CD8A) (AA 22-131) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (AA 1-235) protein (GST tag)CD8A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
CD8a Molecule (CD8A) (Active) protein (His tag)CD8A 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD8a Molecule (CD8A) protein (Fc Tag)CD8A 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
-
缓冲液
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.
-
-
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
-
别名
- CD8a
-
背景
-
Description: T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been implicated in the recognition of monomorphic determinants on major histocompatibility complex (MHC) Class I antigens, and in signal transduction during the course of T-cell activation. Both human and rodent CD8 antigens are comprised of two distinct polypeptide chains, alpha and beta. The Ig domains of CD8 alpha are involved in controlling the ability of CD8 to be expressed. Mutation of B- and F-strand cysteine residues in CD8 alpha reduced the ability of the protein to fold properly and, therefore, to be expressed. Defects in CD8A are a cause of familial CD8 deficiency. Familial CD8 deficiency is a novel autosomal recessive immunologic defect characterized by absence of CD8+ cells, leading to recurrent bacterial infections.
Name: Ly-2, Ly-B, Ly-35, Lyt-2,CD8A
-
基因ID
- 12525
-
UniProt
- P01731
-
途径
- TCR Signaling
抗原
-
