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MME Protein (AA 461-750) (His tag)

This Recombinant MME protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7505418
发货至: 中国

Quick Overview for MME Protein (AA 461-750) (His tag) (ABIN7505418)

抗原

See all MME 蛋白
MME (Membrane Metallo-Endopeptidase (MME))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 461-750

    标记

    This MME protein is labelled with His tag.

    序列

    Met 461-Trp 750

    产品特性

    A DNA sequence encoding the Mouse MME protein (Q61391) (Met 461-Trp 750) was expressed with N-His tag.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    MME (Membrane Metallo-Endopeptidase (MME))

    别名

    MME

    背景

    Abbreviation: MME,CD10,Neprilysin

    Target Synonym: Atriopeptidase,CALLA,Enkephalinase,EPN,NEP,Neprilysin,neprilysin-390,neprilysin-411,SFE,Skin fibroblast elastase

    Background: CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.

    分子量

    Calculated MW: 31.79 kDa

    Observed MW: 32 kDa

    UniProt

    Q61391

    途径

    RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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