IL1RN Protein (AA 27-178) (His tag)
Quick Overview for IL1RN Protein (AA 27-178) (His tag) (ABIN7505391)
抗原
See all IL1RN 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 27-178
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标记
- This IL1RN protein is labelled with His tag.
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序列
- Arg 27-Gln 178
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产品特性
- A DNA sequence encoding the Mouse IL-1ra/IL-1F3 protein (P25085) (Arg27-Gln178) was expressed with a N-His .
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Interleukin 1 Receptor Antagonist (IL1RN) (AA 1-159) protein (GST tag)
IL1RN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Interleukin 1 Receptor Antagonist (IL1RN) (AA 25-178) protein (His tag)IL1RN 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 Receptor Antagonist (IL1RN) proteinIL1RN 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 Receptor Antagonist (IL1RN) (AA 18-332) protein (Fc Tag)IL1RN 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
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别名
- IL-1ra
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背景
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Abbreviation: IL-1ra,IL-1F3
Target Synonym: IL-1RN,IL-1ra,IRAP,IL1 inhibitor,Il1rn,Interleukin-1 Receptor Antagonist Protein
Background: Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and interleukin 1 beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. The mouse Il1rn gene encodes a 178 amino acids (aa) protein with a 26 aa signal peptide. Mouse Il1rn protein shares 26 % and 19 % identity with its homologues IL-1 beta and IL-1 alpha, respectively. Il1rn can Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling, but has no interleukin-1 like activity. Recently, an recombinant human Il1rn protein is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 plays a key role.
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分子量
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Calculated MW: 16.61 kDa
Observed MW: 18 kDa
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UniProt
- P25085
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途径
- NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
抗原
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