CTNNB1 Protein (AA 131-670)
Quick Overview for CTNNB1 Protein (AA 131-670) (ABIN7504998)
抗原
See all CTNNB1 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 131-670
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序列
- Met131-Tyr670
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产品特性
- A DNA sequence encoding the Human Human CTNNB1 Protein(P35222)(131-670)was expressed with a polyhistidine tag at the N-terminus.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
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别名
- CTNNB1
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背景
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Abbreviation: CTNNB1
Target Synonym: Catenin beta-1,Beta-catenin,CTNNB,OK,SW-cl.35,PRO2286
Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.
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分子量
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Calculated MW: 59 kDa
Observed MW: 59 kDa
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UniProt
- P35222
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Tube Formation, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
抗原
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