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IL1RN Protein (AA 26-177)

This Recombinant IL1RN protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7504980
发货至: 中国

Quick Overview for IL1RN Protein (AA 26-177) (ABIN7504980)

抗原

See all IL1RN 蛋白
IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

蛋白类型

Recombinant

宿主

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资源

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大肠杆菌(E. Coli)

纯度

> 90 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 26-177

    序列

    Arg26-Glu177

    产品特性

    A DNA sequence encoding the Human IL-1Ra Protein(P18510)(Arg26-Glu177)was expressed with a polyhistidine tag at the N-terminus.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

    别名

    IL-1Ra

    背景

    Abbreviation: IL-1Ra

    Target Synonym: Interleukin-1 receptor antagonist protein,IL-1RN,IL-1ra,IRAP,ICIL-1RA,IL1 inhibitor,Anakinra,IL1RN,IL1F3,IL1RA

    Background: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

    分子量

    Calculated MW: 19.4 kDa

    Observed MW: 19 kDa

    UniProt

    P18510

    途径

    NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints
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