MME Protein (AA 52-750)
Quick Overview for MME Protein (AA 52-750) (ABIN7504255)
抗原
See all MME 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 52-750
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原理
- Human CD10/MME Protein
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序列
- Tyr52-Trp750
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产品特性
- Recombinant Human CD10/MME Protein is expressed from HEK293 without tag.It contains Tyr52-Trp750.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as 0.22 μm filtered solution in 50 mM MES, 100 mM NaCl, 10 % glycerol ( pH 6.5).
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储存条件
- -80 °C
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储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- MME (Membrane Metallo-Endopeptidase (MME))
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别名
- CD10
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背景
- CD10 is an endopeptidase that degrades various bioactive peptides in the extracellular matrix. In addition to enzymatic degradation, it affects multiple intracellular signal transduction pathways. CD10 expression has been extensively studied in human epithelial cancers of numerous organs and sites. CD10 expression pattern depended on the histotypes of thyroid lesions. When possible metastatic tumours and non-epithelial tumours are excluded, high CD10 expression may be useful in determining whether a primary thyroid carcinoma includes an anaplastic component.
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分子量
- 79.83 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.
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UniProt
- P08473
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途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
抗原
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