NKG2A & CD94 protein (mFc Tag)
Quick Overview for NKG2A & CD94 protein (mFc Tag) (ABIN7488870)
抗原
蛋白类型
宿主
资源
纯度
质量等级
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标记
- mFc Tag
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原理
- Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified)
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序列
- Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94)
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产品特性
- Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1(NKG2A) & O35778-1(CD94).
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内毒素水平
- 1.0 EU per μg
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说明
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This protein carries a mouse IgG2a Fc tag at the C-terminus. (mFc(mIgG2a) The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- NKG2A & CD94
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别名
- NKG2A&CD94
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背景
- CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 Molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells.
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分子量
- 61.0 kDa
抗原
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