Vitronectin Protein (VTN) (His tag)
Quick Overview for Vitronectin Protein (VTN) (His tag) (ABIN7455636)
抗原
See all Vitronectin (VTN) 蛋白蛋白类型
宿主
资源
纯度
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标记
- This Vitronectin protein is labelled with His tag.
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原理
- Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Val62-Leu478 is expressed with a 6His tag at the C-terminus.
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Vitronectin (VTN) (Active) protein (His tag)
VTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Vitronectin (VTN) (AA 1-478) protein (GST tag)VTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vitronectin (VTN) (AA 20-478) protein (His tag)VTN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% by SDS-PAGE SDS
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- Vitronectin (VTN)
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别名
- Vitronectin
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背景
- Vitronectin, also known as VTN, is a large glycoprotein found in blood and the extracellular matrix (ECM). Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Blocking of Hic(a member of the pneumococcal surface protein C (PspC) family) by specific antiserum or genetic deletion significantly reduced pneumococcal binding to soluble and immobilised vitronectin and to Factor H, respectively. In addition, Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
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分子量
- 48.3 KDa
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途径
- Autophagy, Smooth Muscle Cell Migration
抗原
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