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CD40 Ligand Protein (CD40LG) (Fc Tag)

This Recombinant CD40 Ligand protein is expressed in HEK-293 Cells.
产品编号 ABIN7491135
发货至: 中国
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Quick Overview for CD40 Ligand Protein (CD40LG) (Fc Tag) (ABIN7491135)

抗原

See all CD40 Ligand (CD40LG) 蛋白
CD40 Ligand (CD40LG)

蛋白类型

Recombinant

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HEK-293 Cells

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 标记

    This CD40 Ligand protein is labelled with Fc Tag.

    原理

    Recombinant mouse CD40L protein with N-terminal human Fc tag

    特异性

    HFc (Glu99-Ala330) Mouse CD40 Ligand (Gly115-Leu260)

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
  • 想要此Protein的其他选项吗?

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    Product
    表达系统
    Conjugate
    Origin
    价格从
    表达系统 HEK-293 Cells
    Conjugate His tag
    Origin Mouse
    价格从 150,642.20 ¥
    表达系统 Cell-free protein synthesis (CFPS)
    Conjugate Strep Tag
    Origin Mouse
    价格从 145,985.55 ¥

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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    CD40 Ligand

    背景

    Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching (PubMed:1374165).[UniProtKB/Swiss-Prot Function]

    分子量

    predicted molecular mass of 42.1 kDa after removal of the signal peptide. The apparent molecular mass of hFc-CD40L is 40-55 kDa due to glycosylation.

    UniProt

    P27548

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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