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IL-3 Protein (His tag)

This Recombinant IL-3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7447933
发货至: 中国
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Quick Overview for IL-3 Protein (His tag) (ABIN7447933)

抗原

See all IL-3 蛋白
IL-3 (Interleukin 3 (IL-3))

蛋白类型

Recombinant

宿主

  • 22
  • 17
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Cynomolgus

资源

  • 31
  • 6
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  • 3
  • 2
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  • 1
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  • 1
HEK-293 Cells

纯度

90,00 %
  • 标记

    This IL-3 protein is labelled with His tag.

    原理

    Cynomolgus IL-3 Protein, His Tag

    序列

    Ala 20 -Gln 143

    产品特性

    Cynomolgus IL-3, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 20 -Gln 143 (Accession # G7P877-1).

    内毒素水平

    1.0 EU per μg
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  • 说明

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.9 kDa. The protein migrates as 18-27 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    IL-3 (Interleukin 3 (IL-3))

    别名

    IL-3

    背景

    Synonyms:IL3,MCGF,MGC79398,MGC79399,MULTI-CSF,Interleukin-3,Description:Interleukin 3 is also known as IL-3, is a protein that in humans is encoded by the IL3 gene. Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. The IL-3 receptor is a heterodimer of the IL-3 specific α-chain and the common β-chain, βc, which is also used by GM-CSF and IL-5. [3] Binding of IL-3 can also involve substitution of the βc by a βIL-3-chain that appears to be specific for IL-3 . Binding of IL-3 to its cognate receptor(s) induces activation of Jak2, phosphorylation of multiple Stats, and the PI3K/Akt pathway. IL-3 may play an important role in the development of airway inflammation associated with asthma. The human IL-3 gene encodes a protein 152 amino acids long, and the naturally occurring IL-3 is glycosylated. The human IL-3 gene is located on chromosome 5, only 9 kilobases from the GM-CSF gene, and its function is quite similar to GM-CSF.

    分子量

    15.9 kDa

    途径

    JAK/STAT Signaling, Regulation of Carbohydrate Metabolic Process, Autophagy
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