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CRLF2 Protein (AA 25-231) (His tag)

This Recombinant CRLF2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7275802
发货至: 中国

Quick Overview for CRLF2 Protein (AA 25-231) (His tag) (ABIN7275802)

抗原

See all CRLF2 蛋白
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 25-231

    标记

    This CRLF2 protein is labelled with His tag.

    原理

    Human TSLPR Protein

    序列

    Gly25-Lys231

    产品特性

    Recombinant Human TSLPR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly25-Lys231.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human TSLPR, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-TSLPR Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA. See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    别名

    TSLPR

    背景

    TSLP is an epithelial cell-derived cytokine synthesized in response to various stimuli, including protease allergens and microorganisms like viruses and bacteria. Biological functions of TSLP require heterodimer formation between the TSLP receptor (TSLPR) and IL-7 receptor-α, which polarize dendritic cells to induce type 2 inflammation and directly expand and/or activate Th2 cells, group 2 innate lymphoid cells, basophils, and other immune cells.

    分子量

    25.1 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

    UniProt

    Q9HC73-1
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