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TGFB2 Protein (AA 303-414)

This Recombinant TGFB2 protein is expressed in HEK-293 Cells.
产品编号 ABIN7275710
发货至: 中国

Quick Overview for TGFB2 Protein (AA 303-414) (ABIN7275710)

抗原

See all TGFB2 蛋白
TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

蛋白类型

Recombinant

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资源

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HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE
  • 产品特性

    AA 303-414

    原理

    Human Mature TGF beta 2 Protein

    序列

    Ala303-Ser414

    产品特性

    Recombinant Human Mature TGF beta 2 Protein is expressed from HEK293 without tag. It contains Ala303-Ser414.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human Mature TGF beta 2, No Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human TGF-beta RII, mFc Tag with the EC50 of 0.11μg/ml determined by ELISA. See testing image for detail.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCl.

    缓冲液

    Lyophilized from 0.22μm filtered solution in 4 mM HCl. Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

    别名

    TGF beta 2

    背景

    Transforming growth factor beta(2) (TGF-beta(2)), a growth regulator of human lens epithelial cells (HLECs), also regulates the death of these cells. TGF-beta(2)-induced apoptosis in HLECs was preceded by an induction of reactive oxygen species (ROS) and a decrease in glutathione in the intracellular content, indicating that this factor induces oxidative stress in HLECs.

    分子量

    12.7 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

    UniProt

    P61812-1

    途径

    Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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