SEZ6 Protein (AA 20-927) (His tag)
Quick Overview for SEZ6 Protein (AA 20-927) (His tag) (ABIN7275571)
抗原
See all SEZ6 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 20-927
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标记
- This SEZ6 protein is labelled with His tag.
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原理
- Cynomolgus SEZ6 Protein
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序列
- Leu20-His927
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产品特性
- Recombinant Cynomolgus SEZ6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His927.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Cynomolgus SEZ6, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 22.7ng/ml determined by ELISA. See testing image for detail.
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Seizure Related 6 Homolog (SEZ6) (AA 20-925) protein (His tag)
SEZ6 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Seizure Related 6 Homolog (SEZ6) (AA 20-922) protein (His tag)SEZ6 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Seizure Related 6 Homolog (SEZ6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)SEZ6 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- SEZ6 (Seizure Related 6 Homolog (SEZ6))
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别名
- SEZ6
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背景
- Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
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分子量
- 99.11 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Tris-Bis PAGE result.
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UniProt
- A0A2K5WPJ4
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途径
- Synaptic Membrane
抗原
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