LGMN Protein (AA 18-433) (His tag)
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- 抗原 See all LGMN 蛋白
- LGMN (Legumain (LGMN))
- 蛋白类型
- Recombinant
- 产品特性
- AA 18-433
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LGMN protein is labelled with His tag.
- 原理
- Human LGMN Protein
- 序列
- Val18-Tyr433
- 产品特性
- Recombinant Human LGMN Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Val18-Tyr433.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LGMN 蛋白
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Legumain (LGMN) (AA 18-435) protein (His tag)
LGMN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Legumain (LGMN) (AA 1-433) protein (GST tag)LGMN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Legumain (LGMN) (Active) protein (His tag)LGMN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 75 % as determined by SDS-PAGE Active
Legumain (LGMN) (Transcript Variant 2) protein (His tag)LGMN 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- LGMN (Legumain (LGMN))
- 别名
- LGMN (LGMN 产品)
- 背景
- Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer's disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.
- 分子量
- 48.6 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.
- UniProt
- Q99538-1
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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