IL1RAP Protein (AA 21-359) (Fc Tag)
Quick Overview for IL1RAP Protein (AA 21-359) (Fc Tag) (ABIN7275029)
抗原
See all IL1RAP 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 21-359
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标记
- This IL1RAP protein is labelled with Fc Tag.
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原理
- Human IL-1R3/IL-1 RAcP Protein
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序列
- Ser21-Glu359
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产品特性
- Recombinant Human IL-1R3/IL-1 RAcP Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser21-Glu359.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-1R3, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA. See testing image for detail.
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Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-359) protein (His-Avi Tag)
IL1RAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-359) protein (His-Avi Tag,Biotin)IL1RAP 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-367) protein (His tag)IL1RAP 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 1-356) protein (GST tag)IL1RAP 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Interleukin 1 Receptor Accessory Protein (IL1RAP) (AA 21-359) protein (His tag)IL1RAP 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 24 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))
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别名
- IL-1R3
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背景
- IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
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分子量
- 65.8 kDa. Due to glycosylation, the protein migrates to 75-85 kDa based on Tris-Bis PAGE result.
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UniProt
- Q9NPH3-1
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途径
- NF-kappaB Signaling, Growth Factor Binding
抗原
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