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BST2 Protein (AA 49-161) (Fc Tag)

BST2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7273993
发货至: 中国
  • 抗原 See all BST2 蛋白
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    蛋白类型
    Recombinant
    产品特性
    AA 49-161
    宿主
    • 10
    • 5
    • 2
    • 1
    资源
    • 5
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This BST2 protein is labelled with Fc Tag.
    原理
    Human BST2 Protein
    序列
    Asn49-Ser161
    产品特性
    Recombinant Human BST2 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Asn49-Ser161.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human BST2, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-BST2 Antibody, hFc Tag with the EC50 of 60.4ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product BST2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
    别名
    BST2 (BST2 产品)
    别名
    BST2 Protein, CD317 Protein, TETHERIN Protein, 2310015I10Rik Protein, Bst-2 Protein, C87040 Protein, DAMP-1 Protein, GREG Protein, Damp1 Protein, bone marrow stromal cell antigen 2 Protein, bone marrow stromal antigen 2 Protein, BST2 Protein, LOC618737 Protein, Bst2 Protein
    背景
    Interferon-induced BST2 (bone marrow stromal cell antigen 2) inhibits viral replication by tethering enveloped virions to the cell surface to restrict viral release and by inducing the NFKB-dependent antiviral immune response. BST2 expression was significantly increased during porcine epidemic diarrhea virus (PEDV) infection of Vero cells by IRF1 targeting its promoter. Both the BST2 and N protein interacted with the E3 ubiquitin ligase MARCHF8/MARCH8 and the cargo receptor.
    分子量
    40 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    途径
    Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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