BST2 Protein (AA 50-161) (His tag)
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北京 101111
Quick Overview for BST2 Protein (AA 50-161) (His tag) (ABIN667927)
抗原
See all BST2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 50-161
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标记
- This BST2 protein is labelled with His tag.
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序列
- MGSSHHHHHH SSGLVPRGSH MSEACRDGLR AVMECRNVTH LLQQELTEAQ KGFQDVEAQA ATCNHTVMAL MASLDAEKAQ GQKKVEELEG EITTLNHKLQ DASAEVERLR RENQVLSVRI ADKKYYPSSQ DSS
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产品特性
- BST2, 50-161aa, Human, His tag, E.coli
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纯化方法
- > 80% by SDS-PAGE
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- 20 mM Tris-HCl buffer ( pH 8.0) containing 20 % glycerol, 0.1M NaCl, 1 mM DTT
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
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别名
- BST-2/Tetherin
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背景
- BST2, also known as bone marrow stromal antigen 2, is involved in the growth and development of B-cells. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. Initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, tetherin has also been shown to inhibit the release of other viruses such as the Lassa and Marburg virions. Also, this protein may play a role in B-cell activation in rheumatoid arthritis. Recombinant human BST2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
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分子量
- 14.8 kDa (133aa) confirmed by MALDI-TOF
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NCBI登录号
- NP_004326
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途径
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
抗原
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