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CD80 Protein (CD80) (AA 38-246) (His tag)

This Recombinant CD80 protein is expressed in HEK-293 Cells.
产品编号 ABIN7273895
发货至: 中国
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Quick Overview for CD80 Protein (CD80) (AA 38-246) (His tag) (ABIN7273895)

抗原

See all CD80 蛋白
CD80

蛋白类型

Recombinant

生物活性

Active

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小鼠

资源

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HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 38-246

    标记

    This CD80 protein is labelled with His tag.

    原理

    Mouse B7-1/CD80 Protein

    序列

    Val38-Asn246

    产品特性

    Recombinant Mouse B7-1/CD80 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val38-Asn246.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Mouse B7-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse B7-1 is greater than 95% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CD80

    别名

    B7-1

    背景

    Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.

    分子量

    24.6 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.

    UniProt

    Q00609

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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