CD80 Protein (CD80) (AA 38-246) (His tag)
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Quick Overview for CD80 Protein (CD80) (AA 38-246) (His tag) (ABIN7273895)
抗原
See all CD80 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 38-246
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标记
- This CD80 protein is labelled with His tag.
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原理
- Mouse B7-1/CD80 Protein
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序列
- Val38-Asn246
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产品特性
- Recombinant Mouse B7-1/CD80 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val38-Asn246.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Mouse B7-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse B7-1 is greater than 95% as determined by SEC-HPLC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- CD80
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别名
- B7-1
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背景
- Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.
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分子量
- 24.6 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
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UniProt
- Q00609
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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