Quick Overview for CD86 Protein (CD86) (His tag,Biotin) (ABIN7319890)
抗原
See all CD86 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD86 protein is labelled with His tag,Biotin.
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原理
- Recombinant Human B7-2/CD86 (C-Avi-6His) Biotinylated
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序列
- Ala24-Pro247
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产品特性
- Biotinylated Recombinant Human CD86 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro247 is expressed with a Avi, 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD86 (CD86) (AA 26-247) protein (Fc Tag)
CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD86 (CD86) (AA 26-247) protein (His-Avi Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD86 (CD86) (AA 26-240) protein (His tag)CD86 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD86 (CD86) (AA 19-240) protein (His tag)HPLC verified CD86 宿主: Cynomolgus, 猕猴 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) protein (His-Avi Tag,Biotin)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD86 (CD86) (AA 24-246) protein (His-DYKDDDDK-Strep II Tag)CD86 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD86 (CD86) (AA 24-245) (Active) protein (Fc Tag)CD86 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) (Active) protein (His tag)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD86 (CD86) (AA 26-247) (Active) protein (Fc Tag,AVI tag,Biotin)CD86 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
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说明
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55-80 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD86
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别名
- CD86
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背景
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Background: The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. The protein interacts with MARCH8, human herpesvirus 8 MIR2 protein, adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.
Synonym: T-Lymphocyte Activation Antigen CD86, Activation B7-2 Antigen, B70, BU63, CTLA-4 Counter-Receptor B7.2, FUN-1, CD86, CD28LG2
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分子量
- 28.4 kDa
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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