CD27 Protein (His tag)
Quick Overview for CD27 Protein (His tag) (ABIN7321004)
抗原
See all CD27 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD27 protein is labelled with His tag.
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原理
- Recombinant Rhesus macaque CD27/TNFRSF7 Protein (His Tag)
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序列
- Thr21-Ile192
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产品特性
- Recombinant Rhesus macaque CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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说明
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40 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD27 (CD27 Molecule (CD27))
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别名
- CD27/TNFRSF7
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背景
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Background: CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7,belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.
Synonym: CD27 Antigen, CD27L Receptor, T-Cell Activation Antigen CD27, T14, Tumor Necrosis Factor Receptor Superfamily Member 7, CD27, CD27, TNFRSF7
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分子量
- 20.1 kDa
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UniProt
- F7BYS2
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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