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Quick Overview for CD19 Protein (Fc Tag) (ABIN7321005)
抗原
See all CD19 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD19 protein is labelled with Fc Tag.
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原理
- Recombinant Rhesus macaque CD19 Protein (Fc Tag)
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序列
- Pro20-Lys292
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产品特性
- Recombinant Rhesus macaque CD19 is produced by our Mammalian expression system and the target gene encoding Pro20-Lys292 is expressed with a Fc tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD19 Molecule (CD19) (AA 20-291) protein (His tag,FITC)
CD19 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 20-291) (Active) protein (Fc Tag,Biotin)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by reduced SDS-PAGE. Active
CD19 Molecule (CD19) (AA 21-291) protein (His tag)CD19 宿主: 猕猴, Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 20-291) protein (His tag)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 20-291) protein (Fc-His Tag)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD19 Molecule (CD19) (AA 20-291) (Active) protein (His tag,AVI tag,Biotin)CD19 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD19 Molecule (CD19) (AA 19-287) protein (His tag)CD19 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE
CD19 Molecule (CD19) (AA 1-556) protein (GST tag)CD19 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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说明
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80-110 kDa
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD19 (CD19 Molecule (CD19))
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别名
- CD19
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背景
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Background: CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
Synonym: B-Lymphocyte Antigen CD19, B-Lymphocyte Surface Antigen B4, Differentiation Antigen CD19, T-Cell Surface Antigen Leu-12, CD19
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分子量
- 57.2 kDa
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UniProt
- F7F486
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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