Vitronectin Protein (VTN) (His tag)
Quick Overview for Vitronectin Protein (VTN) (His tag) (ABIN7319175)
抗原
See all Vitronectin (VTN) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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标记
- This Vitronectin protein is labelled with His tag.
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原理
- Recombinant Human Vitronectin/VTN Protein (His Tag)(Active)
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序列
- Asp20-Leu478
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产品特性
- Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Asp20-Leu478 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Biological Activity Comment
- Measured by the ability of the immobilized protein to support the adhesion of Jurkat cells.
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Vitronectin (VTN) (Active) protein (His tag)
VTN 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 94 % as determined by SDS-PAGE Active
Vitronectin (VTN) (AA 20-478) protein (His tag)VTN 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90% by SDS-PAGE SDS
Vitronectin (VTN) (AA 1-478) protein (GST tag)VTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Vitronectin (VTN)
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别名
- Vitronectin/VTN
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背景
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Background: Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM, Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site, plus cleavage sites for elastase, thrombin, and plasmin.
Synonym: Vitronectin, VN, S-Protein, Serum-Spreading Factor, V75, VTN
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分子量
- 53.4 kDa
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UniProt
- P04004
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途径
- Autophagy, Smooth Muscle Cell Migration
抗原
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