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Quick Overview for SERPIND1 Protein (His tag) (ABIN7320642)
抗原
See all SERPIND1 蛋白蛋白类型
宿主
资源
纯度
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标记
- This SERPIND1 protein is labelled with His tag.
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原理
- Recombinant Mouse SerpinD1/HCF2 Protein (His Tag)
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序列
- Glu24-Ser478
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产品特性
- Recombinant Mouse Serine Protease Inhibitor-clade D1 is produced by our Mammalian expression system and the target gene encoding Glu24-Ser478 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) (AA 1-499) protein (GST tag)
SERPIND1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) (AA 58-499) protein (His tag)SERPIND1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % SDS
serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) (Active) protein (His tag)SERPIND1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM HEPES,150 mM NaCl, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- SERPIND1 (serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1))
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别名
- SerpinD1/HCF2
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背景
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Background: SerpinD1, also known as heparin cofactor II(HC-II), is a member of Serpin superfamily of the serine proteinase inhibitors. It is a single chain glycoprotein with a size of 66.5 kDa and is secreted from hepatocytes. HC-II acts as a thrombin inhibitor in the coagulation cascade, in a glycosaminoglycan-dependent pathway using the release of a sequestered hirudin-like N-terminal tail for interaction with thrombin. This serpin belongs to multiple member group V2 of vertebrate serpin classification. It has been suggested that HC-II is a predictor of decreased atherosclerosis in the elderly and protective against atherosclerosis in mice. HCII can used as a predictive biomarker and therapeutic target for atherosclerosis.
Synonym: Heparin cofactor 2, Heparin cofactor II, HC-II, Protease inhibitor leuserpin-2, Serpin D1
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分子量
- 53.1 kDa
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UniProt
- P49182
抗原
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