Quick Overview for NEDD8 蛋白 (ABIN7319921)
抗原
See all NEDD8 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human NEDD8
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序列
- Met1-Gly76
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产品特性
- Recombinant Human Neural precursor cell expressed developmentally down-regulated protein 8 is produced by our E.coli expression system and the target gene encoding Met1-Gly76 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (AA 1-81) protein (GST tag)
NEDD8 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 250 mM NaCl, pH 8.0.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
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别名
- NEDD8
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背景
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Background: Human NEDD8 shares 60 % amino acid sequence identity to ubiquitin. The only known substrates of NEDD8 modification are the cullin subunits of SCF ubiquitin E3 ligases. The NEDDylation of cullins is critical for the recruitment of E2 to the ligase complex, thus facilitating ubiquitin conjugation. NEDD8 modification has therefore been implicated in cell cycle progression and cytoskeletal regulation.
Synonym: Neural precursor cell expressed developmentally down-regulated protein 8, NEDD8, Neddylin, Ubiquitin-like protein Nedd8
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分子量
- 8.6 kDa
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UniProt
- Q15843
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途径
- Ubiquitin Proteasome Pathway
抗原
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