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IL-8 Protein (AA 28-99) (His tag)

This Recombinant IL-8 protein is expressed in 大肠杆菌(E. Coli).
产品编号 ABIN7318687
发货至: 中国
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Quick Overview for IL-8 Protein (AA 28-99) (His tag) (ABIN7318687)

抗原

See all IL-8 (IL8) 蛋白
IL-8 (IL8) (Interleukin 8 (IL8))

蛋白类型

Recombinant

生物活性

Active

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资源

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大肠杆菌(E. Coli)

应用范围

Cell Culture (CC)

纯度

> 98 % as determined by reducing SDS-PAGE.
  • 产品特性

    AA 28-99

    标记

    This IL-8 protein is labelled with His tag.

    原理

    Recombinant Human IL-8/CXCL8 Protein

    序列

    Ser28-Ser99

    产品特性

    Recombinant Human Interleukin-8 is produced by our E.coli expression system and the target gene encoding Ser28-Ser99 is expressed.

    过滤

    0.2 μm filtered

    内毒素水平

    < 0.1 EU per μg of the protein as determined by the LAL method.

    Biological Activity Comment

    Measure by its ability to chemoattract PBMC. The ED50 for this effect is <2 ng/mL.
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  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 8.0.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

    有效期

    12 months
  • 抗原

    IL-8 (IL8) (Interleukin 8 (IL8))

    别名

    IL-8/CXCL8

    背景

    CXCL,Interleukin,C-X-C motif chemokine,Chemokine (C-X-C motif) ligand,IL8/CXCL,GCP,NAP,CXCL8,GCP-1,GCP1,IL8,LECT,LUCT,LYNAP,MDNCF,MONAP,NAF,NAP-1,NAP1,3-10C,AMCF-I,IL8/CXCL8,K60,Interleukin-8,IL-8,Emoctakin,C-X-C motif chemokine 8,Chemokine (C-X-C motif) ligand 8,Granulocyte chemotactic protein 1 (GCP-1),Monocyte-derived neutrophil chemotactic factor (MDNCF),(Ala-IL-8)77,(Ser-IL-8)72,9E3,Beta thromboglobulin like protein,CEF-4,chemokine,CXC motif,GCP/IL-8 protein I,GCP/IL-8 protein II,GCP/IL-8 protein III,GCP/IL-8 protein IV,GCP/IL-8 protein V,GCP/IL-8 protein VI,Granulocyte chemotactic protein 1,IL-8(1-77),IL-8(9-77),IL8/NAP1 form I,IL8/NAP1 form II,IL8/NAP1 form III,IL8/NAP1 form IV,IL8/NAP1 form V,IL8/NAP1 form VI,Inteleukin 8,ligand 8,Lymphocyte-derived neutrophil-activating factor,MDNCF-b,MDNCF-c,Monocyte-derived neutrophil chemotactic factor,Monocyte-derived neutrophil-activating peptide,Neutrophil activating peptide 1,Neutrophil activating protein 1,Neutrophil-activating factor,Neutrophil-activating protein 1,Protein 3 10C,Protein 3-10C,SCYB8,Small inducible cytokine subfamily B member 8,T cell chemotactic factor,T-cell chemotactic factor,TSG1,Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 levels are associated with the onset of a variety of disease states.

    分子量

    Calculated MW: 9.3 kDa

    Observed MW: 11 kDa

    基因ID

    3576

    UniProt

    P10145

    途径

    TLR signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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