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IL-18 Protein (His tag)

This Recombinant IL-18 protein is expressed in 人细胞.
产品编号 ABIN7318654
发货至: 中国

Quick Overview for IL-18 Protein (His tag) (ABIN7318654)

抗原

See all IL-18 (IL18) 蛋白
IL-18 (IL18) (Interleukin 18 (IL18))

蛋白类型

Recombinant

宿主

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资源

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人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This IL-18 protein is labelled with His tag.

    原理

    Recombinant Human Interleukin-18/IL-18 Protein (His Tag)

    序列

    Tyr37-Asp193

    产品特性

    Recombinant Human Interleukin-18 is produced by our Mammalian expression system and the target gene encoding Tyr37-Asp193 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Please refer to the printed manual for detailed information.

    缓冲液

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    储存条件

    4 °C,-20 °C,-80 °C

    储存方法

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原

    IL-18 (IL18) (Interleukin 18 (IL18))

    别名

    Interleukin-18/IL-18

    背景

    Background: Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After stimulation with IL-18, natural killer (NK) cells and certain T cells release another important cytokine called interferon-γ (IFN-γ) or type II interferon that plays an important role in activating the macrophages or other cells.

    Synonym: Interleukin-18, Iboctadekin, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma,GIF, IL-18, IL-1g, IL1F4, MGC12320

    分子量

    23.3 kDa

    UniProt

    Q14116

    途径

    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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