Growth Hormone 1 Protein (GH1) (AA 27-217)
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Quick Overview for Growth Hormone 1 Protein (GH1) (AA 27-217) (ABIN7196005)
抗原
See all Growth Hormone 1 (GH1) 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 27-217
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原理
- Recombinant Human GH1/Growth hormone 1 Protein
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序列
- Phe27-Phe217
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产品特性
- A DNA sequence encoding the human GH1 (P01241) (Phe27-Phe217) was expressed.
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过滤
- 0.2 μm filtered
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Biological Activity Comment
- Measured by its ability to promote proliferation of INS-1 cells. The ED50 for this effect is 0.2-1 ng/mL.
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Growth Hormone 1 (GH1) (AA 1-217) protein (GST tag)
GH1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Growth Hormone 1 (GH1) (Active) proteinGH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE Func Active
Growth Hormone 1 (GH1) (AA 27-216) proteinGH1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by reducing SDS-PAGE.
Growth Hormone 1 (GH1) proteinGH1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 98,00% SDS
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile PBS, pH 7.4
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- Growth Hormone 1 (GH1)
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别名
- GH1/Growth hormone 1
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背景
- GH,GH-N,GH1,GHB5,GHN,Growth hormone 1,IGHD1B,hGH-N,The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
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分子量
- 22.1 kDa
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基因ID
- 2688
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UniProt
- P01241
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途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
抗原
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