EGFR Protein (AA 668-1210) (His-GST)
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北京 101111
Quick Overview for EGFR Protein (AA 668-1210) (His-GST) (ABIN7317119)
抗原
See all EGFR 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 668-1210
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标记
- This EGFR protein is labelled with His-GST.
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原理
- Recombinant Human EGFR/ErbB1 Protein (aa 668-1210, His&GST Tag)
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序列
- Met 668-Ala 1210
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产品特性
- A DNA sequence encoding the cytoplasmic domain (Met 668-Ala 1210) of human EGFR (NP_005219) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- The specific activity was determined to be 105 nmol/min/mg using Poly(Glu:Tyr) 4:1 as substrate.
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Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His-Avi Tag)
EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (Biotin,His-Avi Tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (Fc Tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-378) (Active) protein (His tag,AVI tag,Biotin)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Func Active
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (His tag,AVI tag,Biotin)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Epidermal Growth Factor Receptor (EGFR) (AA 1-405) protein (GST tag)EGFR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) protein (His tag)EGFR 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, AM, ADA, IA
Epidermal Growth Factor Receptor (EGFR) (AA 25-645) (Active) protein (His tag)EGFR 宿主: 猕猴 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Epidermal Growth Factor Receptor (EGFR) (AA 669-1210) protein (GST tag)EGFR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Epidermal Growth Factor Receptor (EGFR) (AA 25-647) protein (His tag)EGFR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining. ScA, AM, ADA, IA
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
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储存条件
- -20 °C
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储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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有效期
- 6 months
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- EGFR/ErbB1
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背景
- ERBB;ERBB1;HER1;NISBD2;PIG61;mENA,As a member of the epidermal growth factor receptor (EGFR) family; EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF; amphiregulin; TGF-α; betacellulin; etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation; survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization; the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK; PI3K/PKB and STAT). In addition; EGFR signaling also has been shown to exert action on carcinogenesis and disease progression; and thus EGFR protein is proposed as a target for cancer therapy currently.
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分子量
- 89.1 kDa
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基因ID
- 1956
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NCBI登录号
- NP_005219
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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