EPH Receptor B4 Protein (EPHB4)
Quick Overview for EPH Receptor B4 Protein (EPHB4) (ABIN7195558)
抗原
See all EPH Receptor B4 (EPHB4) 蛋白蛋白类型
生物活性
宿主
资源
纯度
-
-
原理
- Recombinant Human EphB4/HTK Protein (Active)
-
序列
- Met 1-Ala 539
-
产品特性
- The mature form of human EphB4 (NP_004435.3) extracellular domain (Met 1-Ala 539) with quinary-aa peptide (DDDDK) at the C-terminus was expressed and purified.
-
内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
-
Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized human EphB4 at 2 μg/ml (100 μl/well) can bind human EphrinB2 with a linear range of 1-125 ng/ml.
-
-
EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)
EPHB4 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
EPH Receptor B4 (EPHB4) (AA 563-987) (Active) protein (GST tag,His tag)EPHB4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by reducing SDS-PAGE. Active
EPH Receptor B4 (EPHB4) (Active) protein (Fc Tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
EPH Receptor B4 (EPHB4) (AA 1-987) protein (GST tag)EPHB4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)EPHB4 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 85 % by SDS - PAGE. SDS
EPH Receptor B4 (EPHB4) (Active) protein (His tag)EPHB4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 98 % as determined by SDS-PAGE Active
EPH Receptor B4 (EPHB4) (AA 16-539) protein (His tag)EPHB4 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 85% by SDS-PAGE SDS
-
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Please refer to the printed manual for detailed information.
-
缓冲液
- Lyophilized from sterile 100 mM NaCl, 50 mM Tris, pH 7.5
-
储存条件
- 4 °C,-20 °C,-80 °C
-
储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
-
- EPH Receptor B4 (EPHB4)
-
别名
- EphB4/HTK
-
背景
-
Background: Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
Synonym: HTK,MYK1,TYRO11
-
分子量
- 57.7 kDa
-
NCBI登录号
- NP_004435
-
途径
- RTK signaling
抗原
-
