C5A 蛋白
Quick Overview for C5A 蛋白 (ABIN7319677)
抗原
See all C5A (C5a) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Human Complement C5a Protein
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序列
- Thr678-Arg751
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产品特性
- Recombinant Human C5a is produced by our E.coli expression system and the target gene encoding Thr678-Arg751 is expressed.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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Complement Component 5a (C5a) (AA 678-751) protein (His tag)
C5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Tris-Bis PAGE
Complement Component 5a (C5a) (AA 1-77) protein (His tag)C5a 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Complement Component 5a (C5a) (AA 679-751) proteinC5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE.
Complement Component 5a (C5a) (AA 679-755) (Active) protein (His tag)C5a 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 679-751) (Active) protein (Fc Tag)C5a 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 678-751) (Active) proteinC5a 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- C5A (C5a) (Complement Component 5a (C5a))
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别名
- Complement C5a
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背景
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Background: Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 α-chain. Human C5a has four α-helices plus three intrachain disulfide bonds that create a triple loop structure. Human C5a is 60 % and 54 % aa identical to mouse and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2. Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.
Synonym: Complement C5, C5a anaphylatoxin, C5a,CPAMD4,ECLZB,C5Da
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分子量
- 8.4 kDa
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UniProt
- P01031
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途径
- Complement System, Carbohydrate Homeostasis
抗原
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