C5A Protein (AA 678-751)
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北京 101111
Quick Overview for C5A Protein (AA 678-751) (ABIN7319677)
抗原
See all C5A (C5a) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 678-751
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原理
- Recombinant Human Complement C5a Protein
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序列
- Thr678-Arg751
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产品特性
- Recombinant Human C5a is produced by our E.coli expression system and the target gene encoding Thr678-Arg751 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Complement Component 5a (C5a) (AA 678-751) (Active) protein (His tag)
C5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by Bis-Tris PAGE Active
Complement Component 5a (C5a) (AA 1-77) protein (His-IF2DI Tag)C5a 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Complement Component 5a (C5a) (AA 679-755) (Active) protein (His tag)C5a 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 678-751) (Active) proteinC5a 宿主: Cynomolgus 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 679-751) (Active) protein (Fc Tag)C5a 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 679-751) proteinC5a 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- C5A (C5a) (Complement Component 5a (C5a))
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别名
- Complement C5a
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背景
- C5Da,C5a,C5a anaphylatoxin,CPAMD4,Complement C5,ECLZB,Human Complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 α-chain. Human C5a has four α-helices plus three intrachain disulfide bonds that create a triple loop structure. Human C5a is 60 % and 54 % aa identical to mouse and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (C5aR/CD88) and a nonsignaling GPCR termed C5L2. Activation of Cd88 results in neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces release of histamine in basophils and mast cells.
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分子量
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Calculated MW: 8.4 kDa
Observed MW: 12 kDa
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基因ID
- 727
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UniProt
- P01031
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途径
- Complement System, Carbohydrate Homeostasis
抗原
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