M-CSF/CSF1 蛋白
Quick Overview for M-CSF/CSF1 蛋白 (ABIN7321260)
抗原
See all M-CSF/CSF1 (CSF1) 蛋白蛋白类型
宿主
资源
纯度
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原理
- Recombinant Rat M-CSF/CSF1 Protein
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序列
- Gln33-Arg254
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产品特性
- Recombinant Rat Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Gln33-Arg254 is expressed.
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内毒素水平
- <1.0 EU per μg as determined by LAL test.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- M-CSF/CSF1
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背景
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Background: Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
Synonym: Macrophage colony-stimulating factor 1, CSF-1, M-CSF, MCSF, CSF1
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分子量
- 25.2 kDa
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UniProt
- Q8JZQ0
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途径
- RTK signaling
抗原
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