M-CSF/CSF1 Protein (AA 33-254)
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Quick Overview for M-CSF/CSF1 Protein (AA 33-254) (ABIN7321260)
抗原
See all M-CSF/CSF1 (CSF1) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- AA 33-254
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原理
- Recombinant Rat M-CSF/CSF1 Protein
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序列
- Glu33-Arg254
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产品特性
- Recombinant Rat Macrophage colony-stimulating factor 1 is produced by our Mammalian expression system and the target gene encoding Gln33-Arg254 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Not validated for activity
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Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein
CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (Fc Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (His-Avi Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (His tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) (Active) protein (His tag)CSF1 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190) (Active) protein (Biotin,His-Avi Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-190), (Isoform 3) (Active) proteinCSF1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as analyzed by non-reducing SDS-PAGE. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-255) protein (mFc Tag)CSF1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ScA, IA, ADA, AM
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-187) (Active) proteinCSF1 宿主: 小鼠 宿主: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-262) (Active) proteinCSF1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE. CC Active
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- M-CSF/CSF1
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背景
- CSF-1,CSF1,M-CSF,MCSF,Macrophage colony-stimulating factor 1,Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
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分子量
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Calculated MW: 25.2 kDa
Observed MW: 46 kDa
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UniProt
- Q8JZQ0
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途径
- RTK signaling
抗原
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