CD40 Protein (CD40) (Fc Tag)
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Quick Overview for CD40 Protein (CD40) (Fc Tag) (ABIN7321209)
抗原
See all CD40 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD40 protein is labelled with Fc Tag.
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原理
- Recombinant Rat CD40/TNFRSF5 Protein (Fc Tag)
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序列
- Met1-Arg193
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产品特性
- A DNA sequence encoding the rat CD40 (Q4QQW2) (Met1-Arg193) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
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内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method
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CD40 (CD40) (AA 21-193) protein (His-Avi Tag,Biotin)
CD40 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 24-193) protein (His tag)CD40 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 21-193) protein (His tag)CD40 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD40 (CD40) (AA 21-193) protein (mFc-His Tag)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD40 (CD40) (AA 21-193) protein (His-DYKDDDDK-Strep II Tag)CD40 宿主: 人 宿主: HEK-293T Cells Recombinant WB, SDS, ELISA, PI
CD40 (CD40) (AA 24-193) (Active) protein (His tag)CD40 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD40 (CD40) (AA 21-193) (Active) protein (His tag)CD40 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD40 (CD40) (AA 21-193) (Active) protein (Fc Tag,AVI tag,Biotin)CD40 宿主: 人 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
CD40 (CD40) protein (Fc Tag)CD40 宿主: Cynomolgus 宿主: 人细胞 Recombinant > 90 % as determined by reducing SDS-PAGE.
CD40 (CD40) (Active) protein (His tag)CD40 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD40
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别名
- CD40/TNFRSF5
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背景
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Background: CD40, also known as TNFRSF5, is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins. CD40 protein plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 protein is expressed in B cells, dendritic cells, macrophages, endothelial cells, and several tumor cell lines. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3). In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis.Immune CheckpointImmune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: IP Antibodies Immune Checkpoint Detection: FCM Antibodies Immune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets Immunotherapy Cancer Immunotherapy Targeted Therapy
Synonym: CD40;Tnfrsf5
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分子量
- 46.2 kDa
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UniProt
- Q4QQW2
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途径
- NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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