Quick Overview for CD226 Protein (CD226) (His tag) (ABIN7320734)
抗原
See all CD226 蛋白蛋白类型
宿主
资源
纯度
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标记
- This CD226 protein is labelled with His tag.
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原理
- Recombinant Mouse CD226/DNAM-1 Protein (His Tag)
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序列
- Glu19-Pro254
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产品特性
- Recombinant Mouse DNAX Accessory Molecule-1 is produced by our Mammalian expression system and the target gene encoding Glu19-Pro254 is expressed with a 6His tag at the C-terminus.
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内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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CD226 (CD226) (AA 19-247) protein (Fc Tag)
CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-252) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD226 (CD226) (AA 19-247) protein (His-Avi Tag,Biotin)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by SEC-HPLC
CD226 (CD226) (AA 19-247) protein (mFc-His Tag)CD226 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. ELISA
CD226 (CD226) (AA 19-252) (Active) protein (His tag)CD226 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
CD226 (CD226) (AA 19-247) protein (hIgG-His-tag)CD226 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 90% by SDS-PAGE SDS
CD226 (CD226) (Active) protein (His tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 97 % as determined by SDS-PAGE Active
CD226 (CD226) (Active) protein (Fc Tag)CD226 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
CD226 (CD226) (AA 19-254) protein (Fc Tag)CD226 宿主: 小鼠 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please refer to the printed manual for detailed information.
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缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
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储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- CD226
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别名
- CD226/DNAM-1
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背景
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Background: Mouse DNAX accessory molecule-1(DNAM-1) is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily. As an activating receptor, it interacts with the ligands CD155 and CD112, and activates natural killer (NK) cells via its immu-noreceptor tyrosine-based activatory motif (ITAM). Mature mouse DNAM-1 has extracellular domain (ECD) that contains two Ig-like C2-set domains, and possesses a cytoplasmic region that contains motifs for binding PDZ domains. DNAM-1 is expressed on several lymphoid and myeloid cell types and interacts with CD155/PVR and Nectin-2/CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, induces dendritic cell maturation, initiates megakaryocyte and activated platelet adhesion to vascular endothelial cells, and stimulates monocyte extravasation? Conversely, it inhibits the formation of osteoclasts. Platelet-endothelium interactions that are mediated by DNAM-1 enable the metastasis of tumor cells to the lung.
Synonym: CD226 antigen, platelet and T cell activation antigen 1, CD226 Molecule, DNAM1 adhesion glycoprotein, DNAM-1,DNAX accessory molecule-1, DNAX accessory molecule 1, PTA1, T lineage-specific activation antigen 1 antigen, CD226, PTA1, TLiSA1,BC051526,DNAM-1,DNAM1,Pta1,TLiSA1
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分子量
- 27.6 kDa
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NCBI登录号
- NP_848802
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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