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Cathepsin B Protein (CTSB) (His tag)

CTSB 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318252
发货至: 中国
  • 抗原 See all Cathepsin B (CTSB) 蛋白
    Cathepsin B (CTSB)
    蛋白类型
    Recombinant
    宿主
    • 18
    • 10
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    资源
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    人细胞
    标记
    This Cathepsin B protein is labelled with His tag.
    原理
    Recombinant Human Cathepsin B/CTSB Protein (His Tag)
    序列
    Arg18-Ile339
    产品特性
    Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product CTSB 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Cathepsin B (CTSB)
    别名
    Cathepsin B/CTSB (CTSB 产品)
    别名
    APPS Protein, CPSB Protein, CB Protein, apps Protein, cpsb Protein, LOC692390 Protein, CTSB Protein, cathepsin B Protein, cathepsin B S homeolog Protein, CTSB Protein, Ctsb Protein, ctsb.S Protein, LOC692390 Protein
    背景

    Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

    Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB

    分子量
    36.9 kDa
    UniProt
    P07858
    途径
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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