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Cathepsin B Protein (CTSB) (His tag)

This Recombinant Cathepsin B protein is expressed in 人细胞.
产品编号 ABIN7318252
发货至: 中国

Quick Overview for Cathepsin B Protein (CTSB) (His tag) (ABIN7318252)

抗原

See all Cathepsin B (CTSB) 蛋白
Cathepsin B (CTSB)

蛋白类型

Recombinant

宿主

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资源

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人细胞

纯度

> 95 % as determined by reducing SDS-PAGE.
  • 标记

    This Cathepsin B protein is labelled with His tag.

    原理

    Recombinant Human Cathepsin B/CTSB Protein (His Tag)

    序列

    Arg18-Ile339

    产品特性

    Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.

    内毒素水平

    < 1.0 EU per μg as determined by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Frozen, Liquid

    缓冲液

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

    储存条件

    -20 °C

    储存方法

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原

    Cathepsin B (CTSB)

    别名

    Cathepsin B/CTSB

    背景

    Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

    Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB

    分子量

    36.9 kDa

    UniProt

    P07858

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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