BDNF Protein (AA 129-247) (His tag)
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北京 101111
Quick Overview for BDNF Protein (AA 129-247) (His tag) (ABIN7319738)
抗原
See all BDNF 蛋白蛋白类型
生物活性
宿主
资源
应用范围
纯度
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产品特性
- AA 129-247
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标记
- This BDNF protein is labelled with His tag.
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原理
- Recombinant Human/Mouse/Rat BDNF Protein
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序列
- His129-Arg247
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产品特性
- Recombinant Human/Mouse/Rat BDNF is produced by our E.coli expression system and the target gene encoding His129-Arg247 is expressed.
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过滤
- 0.2 μm filtered
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内毒素水平
- < 0.1 EU per μg of the protein as determined by the LAL method.
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Biological Activity Comment
- Measure by its ability to induce proliferation in BaF3 cells transfected with TrkB. The ED50 for this effect is <2 ng/mL.
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Brain-Derived Neurotrophic Factor (BDNF) (Active) protein (Biotin)
BDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant WB, CC, in vivo, Diff, CyTox, AD, FM, IF, LCI Active
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-255) protein (GST tag)BDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) protein (GST tag)BDNF 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Brain-Derived Neurotrophic Factor (BDNF) proteinBDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 97,00% SDS
Brain-Derived Neurotrophic Factor (BDNF) (AA 137-237), (partial) protein (GST tag)BDNF 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 90 % SDS, ELISA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
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Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization. -
储存条件
- 4 °C,-20 °C,-80 °C
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储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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有效期
- 12 months
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- BDNF
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背景
- Abrineurin,BDNF,Brain-Derived Neurotrophic Factor,Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
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分子量
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Calculated MW: 14.5 kDa
Observed MW: 14 kDa
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基因ID
- 627
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UniProt
- P23560
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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