PD-L1 Protein (His tag)
Quick Overview for PD-L1 Protein (His tag) (ABIN7121291)
抗原
See all PD-L1 蛋白蛋白类型
宿主
资源
纯度
质量等级
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标记
- This PD-L1 protein is labelled with His tag.
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原理
- Canine PD-L1 / B7-H1 Protein, His Tag (MALS verified)
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序列
- Phe 19 - Arg 236
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产品特性
- Canine PD-L1, His Tag (PDL-C52H4) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Arg 236 (Accession # E2RKZ5-1).
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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应用备注
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 35-50 kDa under reducing (R) condition due to glycosylation.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- -20°C
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- PD-L1 (CD274 (PD-L1))
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别名
- PD-L1 / B7-H1
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背景
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Synonyms: PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1,
Description: Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression. -
分子量
- 26.6 kDa
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NCBI登录号
- NP_001278901
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途径
- Cancer Immune Checkpoints
抗原
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