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PD-L1 Protein (His tag)

This Recombinant PD-L1 protein is expressed in HEK-293 Cells.
产品编号 ABIN7121291
发货至: 中国

Quick Overview for PD-L1 Protein (His tag) (ABIN7121291)

抗原

See all PD-L1 蛋白
PD-L1 (CD274 (PD-L1))

蛋白类型

Recombinant

宿主

  • 50
  • 19
  • 6
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  • 4
  • 3
  • 1

资源

  • 49
  • 10
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  • 5
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  • 2
  • 1
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  • 1
HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.

质量等级

MALS verified
  • 标记

    This PD-L1 protein is labelled with His tag.

    原理

    Canine PD-L1 / B7-H1 Protein, His Tag (MALS verified)

    序列

    Phe 19 - Arg 236

    产品特性

    Canine PD-L1, His Tag (PDL-C52H4) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Arg 236 (Accession # E2RKZ5-1).

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 应用备注

    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 35-50 kDa under reducing (R) condition due to glycosylation.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    PD-L1 (CD274 (PD-L1))

    别名

    PD-L1 / B7-H1

    背景

    Synonyms: PD-L1,CD274,B7-H1,PDCD1L1,PDCD1LG1,
    Description: Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

    分子量

    26.6 kDa

    NCBI登录号

    NP_001278901

    途径

    Cancer Immune Checkpoints
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