SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (D3L, G204R, R203K, S235F) (His tag)
Quick Overview for SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (D3L, G204R, R203K, S235F) (His tag) (ABIN6971314)
抗原
See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) 蛋白蛋白类型
宿主
资源
纯度
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产品特性
- D3L, G204R, R203K, S235F
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标记
- This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.
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原理
- SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag
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序列
- AA 1-419
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产品特性
- SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (D3L, S235F) (Accession # QHO62115.1(D3L, S235F). D3L/ S235F were identified in the SARS-CoV-2 variant (known as 20B/501Y.V1, VOC 202012/01, or B.1.1.7 lineage) which emerged in the United Kindom.
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内毒素水平
- Less than 1.0 EU per μg by the LAL method.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C,-80 °C
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储存方法
- For long term storage, the product should be stored at lyophilized state at -20°C or lower.
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有效期
- 12 months
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- SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
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别名
- SARS-CoV-2 Nucleocapsid
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物质类
- Viral Protein
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背景
- Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
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分子量
- 47.4 kDa
抗原
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