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SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (D3L, G204R, R203K, S235F) (His tag)

This Recombinant SARS-CoV-2 Nucleocapsid protein is expressed in HEK-293 Cells.
产品编号 ABIN6971314
发货至: 中国

Quick Overview for SARS-CoV-2 Nucleocapsid Protein (SARS-CoV-2 N) (D3L, G204R, R203K, S235F) (His tag) (ABIN6971314)

抗原

See all SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N) 蛋白
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

蛋白类型

Recombinant

宿主

  • 39
  • 6
  • 1
SARS Coronavirus-2 (SARS-CoV-2)

资源

  • 21
  • 14
  • 1
  • 1
  • 1
  • 1
HEK-293 Cells

纯度

>90 % as determined by SDS-PAGE.
  • 产品特性

    D3L, G204R, R203K, S235F

    标记

    This SARS-CoV-2 Nucleocapsid protein is labelled with His tag.

    原理

    SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag

    序列

    AA 1-419

    产品特性

    SARS-CoV-2 Nucleocapsid protein (D3L, S235F), His Tag is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ala 419 (D3L, S235F) (Accession # QHO62115.1(D3L, S235F). D3L/ S235F were identified in the SARS-CoV-2 variant (known as 20B/501Y.V1, VOC 202012/01, or B.1.1.7 lineage) which emerged in the United Kindom.

    内毒素水平

    Less than 1.0 EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    PBS, pH 7.4

    储存条件

    -20 °C,-80 °C

    储存方法

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    有效期

    12 months
  • 抗原

    SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)

    别名

    SARS-CoV-2 Nucleocapsid

    物质类

    Viral Protein

    背景

    Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology, 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

    分子量

    47.4 kDa
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