K-RAS Protein (AA 2-185) (Fc Tag)
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- 抗原 See all K-RAS (KRAS) 蛋白
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 蛋白类型
- Recombinant
- 产品特性
- AA 2-185
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This K-RAS protein is labelled with Fc Tag.
- 原理
- Recombinant Human KRAS with C-terminal human Fc tag
- 特异性
- KRAS (Thr2-Cys185) hFc (Glu99-Ala330)
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product KRAS 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- K-RAS (KRAS) (GTPase Kras (KRAS))
- 别名
- KRAS (KRAS 产品)
- 物质类
- Viral Protein
- 背景
- This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
- 分子量
- predicted molecular mass of 47.1 kDa after removal of the signal peptide. The apparent molecular mass of KRAS-hFc is 35-55 kDa due to glycosylation.
- UniProt
- P01116
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