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VEGFR2/CD309 Protein (AA 20-764) (His tag)

This Recombinant VEGFR2/CD309 protein is expressed in HEK-293 Cells.
产品编号 ABIN6964112
发货至: 中国

Quick Overview for VEGFR2/CD309 Protein (AA 20-764) (His tag) (ABIN6964112)

抗原

See all VEGFR2/CD309 (VEGFR2) 蛋白
VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

蛋白类型

Recombinant

宿主

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资源

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HEK-293 Cells

纯度

The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
  • 产品特性

    AA 20-764

    标记

    This VEGFR2/CD309 protein is labelled with His tag.

    原理

    Recombinant human VEGFR2 Protein with C-terminal 6xHis tag

    特异性

    VEGFR2 (Ala20-Glu764) 6xHis tag

    产品特性

    Extracellular Domain Protein

    纯化方法

    Purified from cell culture supernatant by affinity chromatography
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    有效期

    12 months
  • 抗原

    VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

    别名

    VEGFR2

    背景

    Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]

    分子量

    predicted molecular mass of 84.1kDa after removal of the signal peptide.The apparent molecular mass of VEGFR2-His is 130-250 kDa due to glycosylation.

    基因ID

    3791

    UniProt

    P35968

    途径

    RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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