ROR2 Protein (AA 34-403) (His tag)
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Quick Overview for ROR2 Protein (AA 34-403) (His tag) (ABIN6964076)
抗原
See all ROR2 蛋白蛋白类型
宿主
资源
应用范围
纯度
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产品特性
- AA 34-403
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标记
- This ROR2 protein is labelled with His tag.
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原理
- Recombinant human ROR2 Protein with C-terminal 6xHis tag
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特异性
- ROR2(Glu34-Gly403) 6xHis tag
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产品特性
- Extracellular Domain Protein
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纯化方法
- Purified from cell culture supernatant by affinity chromatography
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Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) (Active) protein (His-Avi Tag)
ROR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) (Active) protein (hFc Tag)ROR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) (Active) protein (Biotin,His-Avi Tag)ROR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 34-403) protein (His tag)ROR2 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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应用备注
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Extracellular Domain Proteins (ECD) can be used as:
- Immunogens for antibody drug development
- Reagents used for CAR-T positive cell monitoring
- Reagents for antibody screening and functional testing
- Reagents for antibody affinity measurement
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说明
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The protein was produced using HEK293 mammalian cell secretion expression system to ensure the close-to-native structures and post-translational modifications of the target protein.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Please see Certificate of Analysis for specific instructions of reconstitution.
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缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
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有效期
- 12 months
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- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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别名
- ROR2
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背景
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ROR2,NTRKR2
The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance. -
分子量
- predicted molecular mass of 42.2 kDa after removal of the signal peptide.The apparent molecular mass of ROR2-His is 55-70 kDa due to glycosylation.
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基因ID
- 4920
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UniProt
- Q01974
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途径
- RTK signaling, WNT signaling
抗原
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